You may feel some slight abdominal cramping for a couple of days after placement. The cramping should be mild and respond well to pain medication.

During and right after Eloira is placed, you may experience dizziness, or other symptoms from low blood pressure. These symptoms usually pass very quickly.

In most cases, there are no complications. However, as with any medical procedure, some complications have been reported when choosing an intrauterine contraceptive:

1. Perforation (puncture of the uterine wall) may rarely occur at the time of insertion, although sometimes it may be discovered only later. Perforation occurs in less than 1 per 1000 insertions
2. Infection at the time of insertion
3. Expulsion, which means that the contractions of the uterus push Eloira out partially or completely. If this occurs, it usually happens in the first month of use. Therefore it is important you visit your healthcare provider 4 – 12 weeks after the placement to confirm that the IUS is in place and learn for yourself how to check for the presence of the threads

To minimize these complications your healthcare provider has been trained in placing Eloira. The use of correct and sterile placement techniques helps to prevent these complications.

Medical treatments and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with intrauterine systems such as Eloira, although not everyone will experience them:

1. Change in menstrual bleeding, such as spotting, lighter bleeding, irregular bleeding or stopping of bleeding
2. Pelvic or abdominal pain
3. Development of cysts in the ovaries. These usually resolve without treatment
4. Headache
5. Breast tenderness
6. Skin changes (acne)

Most of these side effects are only seen temporarily in the first 3 to 6 months after placing intrauterine systems.

Talk to your healthcare provider if you experience any of these symptoms.

Studies have shown that women do not gain more weight while using intrauterine systems more than those using a non-hormonal method of contraception such as copper intrauterine devices.

Studies have not provided evidence of an increased risk of development of breast cancer during the use of intrauterine systems such as Eloira. Since the occurrence of breast cancer increases with age, you should examine your breasts regularly especially if you are older than 40 years.

Intrauterine systems such as Eloira are known to cause some changes to bleeding patterns. For the first 3 to 6 months, your monthly period may become irregular. You may also experience spotting or light bleeding. After your body adjusts, the number of bleeding days is likely to decrease, and you may even find that your periods stop altogether for as long as the intrauterine system is in place. This is not harmful for your body.

Around the end of the third month of use, you may see up to a 75% reduction in the amount of menstrual bleeding. Women with heavy menstrual bleeding before the placement of the intrauterine system experience even higher reduction, up to 97% of their bleeding amount.

By the end of year one, about one out of five users have no bleeding at all. This is not unhealthy for your body. Your periods will return once the intrauterine system is removed.

Abnormal or irregular bleeding from the uterus is referred to as Dysfunctional Uterine Bleeding (DUB). Levonorgestrel intrauterine systems like Eloira are known to help with heavy bleeding / DUB.

A systematic review of the literature on menstrual effects found that all included studies demonstrated a significant reduction of menstrual blood loss or "menstrual disturbance score" and most showed improved iron levels with the use of an Intrauterine System.
Effective medical therapies for DUB according to ACOG (American College of Obstetricians and Gynecologists) include the levonorgestrel intrauterine system.

After placing Eloira, a further appointment should be made for four to 12 weeks later to check for correct placement and any problems. Yearly checks are advised after this appointment.

Eloira needs to be replaced with a new system every 5 years.